How CBD Works in Dogs

The Endocannabinoid system in dogs is part of what maintains the natural balance in the body and it is usually stimulated by endocannabinoids (which are produced internally). However, the endocannabinoid system can also be stimulated by external cannabinoids, including Cannabidiol (CBD) – the non-psychoactive compound found in industrial hemp.

 

CANNABINOID CB1 & CB2 RECEPTOR LOCATIONS IN DOGS

How CBD Functions

The Endocannabinoid System (ECS) is a group of endogenous cannabinoid receptors that are located throughout the body. It has two kinds of receptors: CB1 & CB2. CB1 receptors are mostly in the brain and central nervous system. CB2 receptors are mostly in peripheral organs, especially immune cells.

CB1

Brain

Lungs

Vascular System

Muscles

Gastrointestinal Tract

Reproductive Organs

CB1 & CB2

Immune system

Liver

Bone marrow

Pancreas

Brainstem

CB2

Spleen

Bones

Skin

Glial Cells (Parts of the Brain)

Cannabinoid Receptor Locations in the Dog Brain

CEREBRAL CORTEX

Plays a role in memory, thinking, awareness and consciousness

HYPOTHALAMUS

Governs metabolic processes such as appetite

AMYGDALA

Plays a role in emotions

HIPPOCAMPUS

Is key to memory storage and recall

BASAL GANGLIA

Governs motor skills and learning

CEREBELLUM

Governs coordination and muscle control

BRAIN STEM

Controls many basic functions including vomiting reflex, blood pressure and heart rate. Also plays a role in pain sensation, muscle tone, and movement